Status: Confirmed ARS: Confirmed by ARS assay and identified by 10 genome-wide studies.
Genomic Location:
Chr4:46181-46237
Within convergent intergenic space between YDL229W and YDL227C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS confirmed.
Helical Stability: Minimum -149.3 ΔG° (kcal/mol) at location 46231.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 36.5 min.
Yabuki et al. (2002) — Trep: 27.4 min.
Alvino et al. (2007) — Peak first observed at 17.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at IV-46 has unique ID: 94
ARS at IV-46 has unique ID: 94
Chr4:46181-46237
None curated.
Chr4:45919-46272
Chr4:44390-48176
Chr4:45200-47700 (orc2-1/wt peak ratio: 0.58)
Chr4:46285-46295
Chr4:45800-47300 (orc1-bah-delta/wt peak ratio: 0.63)
Chr4:43761 (Trep: 36.5 min.) (Confidence: 9)
Chr4:46791 (Trep: 27.4 min.)
Chr4:47429 (Peak first observed at 17.5 min.)
Chr4:47333 (Activity detected in: rad53)
Chr4:46181-46237 (Activity detected in: ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at IV-46 has unique ID: 94
Kearsey (1984): | A | T | T | T | A | A | T | A | T | T | T | T |
Xu et al. (2006): | A | A | A | T | T | T | A | A | T | A | T | T | T | T | G | G | A | T | G | A | A | A | A | A | A | A | C | C | A | T | T | T | T | T | ||||||||
Eaton et al. (2010): | A | A | A | T | T | T | A | A | T | A | T | T | T | T | G | G | A | T | G | A | A | A | A | A | A | A | C | C | A | T | T | T | T | |||||||||
ACS LOGO: | ![]() |
ARS at IV-46 has unique ID: 94
ARS at IV-46 has unique ID: 94
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at IV-46 has unique ID: 94
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | BMC Genomics
None identified.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at IV-46 has unique ID: 94