Status: Confirmed ARS: Confirmed by ARS assay and identified by 9 genome-wide studies.
Genomic Location:
Chr1:124350-124599
Within divergent intergenic space between YAL016C-B and YAL016W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -135.4 ΔG° (kcal/mol) at location 124590.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 29.9 min.
Yabuki et al. (2002) — Trep: 28.1 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at I-124 has unique ID: 9
ARS at I-124 has unique ID: 9
Chr1:124350-124599
None curated.
Chr1:124299-124883
Chr1:123305-125545
Chr1:123000-125700 (orc2-1/wt peak ratio: 0.74)
Chr1:124515-124525
Chr1:123800-125300 (orc1-bah-delta/wt peak ratio: 0.60)
Chr1:121834 (Trep: 29.9 min.) (Confidence: 2)
Chr1:125269 (Trep: 28.1 min.)
Chr1:124000 (Activity detected in: rad53)
Chr1:124350-124599 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at I-124 has unique ID: 9
Nieduszynski et al. (2006): | A | T | A | T | T | T | A | A | G | T | C | T | T | G | A | T | ||||||||||||||||||||||||||
Eaton et al. (2010): | A | T | T | T | T | T | T | A | T | A | T | T | T | A | A | G | T | C | T | T | G | A | T | T | A | A | C | T | G | C | T | T | T | |||||||||
ACS LOGO: |
ARS at I-124 has unique ID: 9
Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S. cerevisiae | T | C | T | A | A | A | T | A | T | G | T | A | A | A | T | T | T | T | T | T | A | T | A | T | T | T | A | A | G | T | C | T | T | G | A | T | T | A | A | C | T | G | C | T | T | T | G | G | A | T | G | C | T | G | T | A |
S. mikatae | G | C | T | A | T | A | C | T | T | G | T | A | A | T | T | T | T | T | T | T | A | T | G | T | T | T | A | A | G | T | G | T | T | A | A | T | A | A | T | T | T | G | T | T | T | T | G | G | T | T | G | C | A | T | T | G |
S. paradoxus | A | T | T | G | A | A | T | A | T | G | T | A | - | - | G | T | T | T | T | T | A | T | A | T | T | T | A | A | G | T | C | T | T | A | A | T | T | G | G | C | T | G | C | T | T | T | A | G | - | T | G | T | C | A | T | A |
S. bayanus | T | A | T | A | T | A | T | T | C | G | T | A | A | T | A | T | T | T | T | T | A | T | A | T | T | T | A | A | G | T | C | T | T | G | A | T | T | A | G | C | C | G | C | T | T | G | G | C | - | - | - | - | - | - | - | - |
* | : | * | : | : | * | * | * | : | * | * | * | * | * | * | * | : | * | * | * | * | * | * | * | : | * | * | * | * | : | : | : | : | * | : | * | * | : | : | : | : | : | : |
ARS at I-124 has unique ID: 9
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at I-124 has unique ID: 9
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | Genes Dev.
ARS at I-124 has unique ID: 9