Status: Confirmed ARS: Confirmed by ARS assay and 2D gel and identified by 10 genome-wide studies.
Genomic Location:
Chr14:250259-250506
Within divergent intergenic space between YNL211C and YNL210W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS confirmed.
Helical Stability: Minimum -141.0 ΔG° (kcal/mol) at location 250429.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 29.1 min.
Yabuki et al. (2002) — Trep: 29.0 min.
Alvino et al. (2007) — Peak first observed at 17.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at XIV-250 has unique ID: 514
ARS at XIV-250 has unique ID: 514
Chr14:250259-250506
Chr14:248811-251501
Chr14:247554-252796
Chr14:247554-252796
Chr14:250314-250930
Chr14:249305-251235
Chr14:250300-251000 (orc2-1/wt peak ratio: 0.22)
Chr14:250395-250405
Chr14:250325-251075 (orc1-bah-delta/wt peak ratio: 0.23)
Chr14:250798 (Trep: 29.1 min.) (Confidence: 5)
Chr14:249469 (Trep: 29.0 min.)
Chr14:251200 (Peak first observed at 17.5 min.)
Chr14:249333 (Activity detected in: rad53)
Chr14:250259-250506 (Activity detected in: mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at XIV-250 has unique ID: 514
| Friedman et al. (1996): | A | T | T | T | G | T | A | T | T | T | A |
| Nieduszynski et al. (2006): | A | A | T | T | T | T | T | A | C | G | G | T | T | T | T | T | ||||||||||||||||||||||||||
| Xu et al. (2006): | A | C | A | A | T | T | T | G | T | A | T | T | T | A | G | T | T | G | G | T | G | T | G | A | C | C | T | C | A | A | A | T | T | T | ||||||||
| Eaton et al. (2010): | A | C | A | A | T | T | T | G | T | A | T | T | T | A | G | T | T | G | G | T | G | T | G | A | C | C | T | C | A | A | A | T | T | |||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at XIV-250 has unique ID: 514
| Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | A | T | T | T | A | G | T | T | G | G | T | G | T | G | A | C | C | T | C | A | A | A | T | T | T | T | T | A | C | G | G | T | T | T | T | T | T | G | A | A | A | A | G | A | A | C | C | C | G | T | T | A | T | G | A | A |
| S. kudriavzevii | G | T | T | T | A | G | T | T | G | - | - | T | T | G | A | T | A | G | A | A | T | G | T | T | T | T | T | A | T | G | A | T | C | A | T | T | G | A | A | A | A | A | A | A | A | A | A | G | G | T | T | T | A | G | A | A |
| S. mikatae | G | T | T | T | A | G | T | T | G | G | G | G | C | A | A | C | A | A | A | A | G | A | T | A | T | A | T | T | T | G | T | T | C | C | T | T | C | A | A | A | A | A | G | G | G | C | G | C | - | - | - | - | T | T | G | A |
| S. paradoxus | A | T | A | T | A | G | T | T | A | A | T | C | T | G | A | C | G | T | C | T | C | A | T | A | T | T | T | T | T | G | G | T | T | C | T | G | C | A | A | A | A | A | G | T | A | C | C | C | G | T | T | A | G | A | G | C |
| S. bayanus | G | T | T | T | A | G | T | T | A | G | T | G | T | A | A | - | - | - | - | - | - | - | - | - | - | - | T | T | T | G | T | A | T | T | T | T | A | A | G | A | A | A | A | T | T | T | C | G | G | A | T | A | T | G | A | A |
| * | : | * | * | * | * | * | : | * | : | : | : | : | * | : | * | : | * | : | : | : | : | * | * | * | : | : | : | |||||||||||||||||||||||||||||
ARS at XIV-250 has unique ID: 514
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at XIV-250 has unique ID: 514
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PubMed | PubMed Central | Genes Dev.
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PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at XIV-250 has unique ID: 514
