Status: Confirmed ARS: Confirmed by ARS assay and identified by 10 genome-wide studies.
Genomic Location:
Chr1:70258-70491
Within divergent intergenic space between YAL039C and YAL038W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -153.6 ΔG° (kcal/mol) at location 70438.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 33.3 min.
Yabuki et al. (2002) — Trep: 28.9 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at I-70 has unique ID: 5
ARS at I-70 has unique ID: 5
Chr1:70258-70491
None curated.
Chr1:69532-70662
Chr1:69767-74608
Chr1:70100-71000 (orc2-1/wt peak ratio: 0.59)
Chr1:70695-70705
Chr1:69950-71075 (orc1-bah-delta/wt peak ratio: 0.38)
Chr1:66295 (Trep: 33.3 min.) (Confidence: 8)
Chr1:73769 (Trep: 28.9 min.)
Chr1:72714 (Peak first observed at 12.5 min.)
Chr1:74333 (Activity detected in: rad53)
Chr1:70258-70491 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at I-70 has unique ID: 5
| Nieduszynski et al. (2006): | T | T | T | T | T | T | A | T | G | T | T | T | A | G | A | A | ||||||||||||||||||||||||||
| Xu et al. (2006): | T | T | T | T | T | T | A | T | G | T | T | T | A | G | A | A | A | C | A | A | A | A | T | T | T | C | C | C | C | G | A | G | A | G | ||||||||
| Eaton et al. (2010): | A | T | T | T | T | T | T | A | T | G | T | T | T | A | G | A | A | A | C | A | A | A | A | T | T | T | C | C | C | C | G | A | G | |||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at I-70 has unique ID: 5
| Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | T | C | T | T | T | T | T | T | G | C | T | G | T | T | G | C | T | T | T | A | T | T | T | T | T | T | A | T | G | T | T | T | A | G | A | A | A | C | A | A | A | A | T | T | T | C | C | C | C | G | A | G | A | G | A | A |
| S. kudriavzevii | C | C | T | T | T | T | T | T | T | T | T | T | T | T | - | - | - | T | T | T | T | T | T | T | T | T | A | T | G | T | T | C | G | G | G | C | G | T | A | A | A | T | T | C | T | T | C | C | T | T | T | C | C | A | G | G |
| S. mikatae | T | C | T | T | T | T | T | T | G | C | T | T | T | A | G | C | - | T | T | G | T | T | T | T | T | T | A | T | G | T | T | T | A | G | A | C | A | T | A | A | A | A | C | T | C | C | G | C | C | T | T | G | A | A | G | A |
| S. paradoxus | A | C | T | T | T | T | T | T | T | A | T | C | C | T | G | C | T | T | C | A | C | T | T | T | T | T | A | T | G | T | T | T | A | G | A | T | A | C | A | A | A | A | T | T | T | C | C | C | C | G | A | G | A | A | T | G |
| * | * | * | * | * | * | * | * | : | : | : | : | * | : | : | * | * | * | * | * | * | * | * | * | * | : | : | * | : | : | * | * | * | : | : | : | : | : | : | * | : | : | : | ||||||||||||||
ARS at I-70 has unique ID: 5
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at I-70 has unique ID: 5
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at I-70 has unique ID: 5
