Status: Confirmed ARS: Confirmed by ARS assay and identified by 10 genome-wide studies.
Genomic Location:
Chr12:412668-412897
Within tandem intergenic space between YLR134W and YLR135W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -140.9 ΔG° (kcal/mol) at location 412668.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 21.4 min.
Yabuki et al. (2002) — Trep: 22.0 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at XII-413 has unique ID: 414
ARS at XII-413 has unique ID: 414
Chr12:412668-412897
None curated.
Chr12:412415-413282
Chr12:411005-413705
Chr12:412100-413500 (orc2-1/wt peak ratio: 0.23)
Chr12:412875-412885
Chr12:412325-413525 (orc1-bah-delta/wt peak ratio: 0.69)
Chr12:410432 (Trep: 21.4 min.) (Confidence: 9)
Chr12:412804 (Trep: 22.0 min.)
Chr12:412880 (Peak first observed at 12.5 min.)
Chr12:413750 (Activity detected in: wild-type, rad53)
Chr12:412668-412897 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at XII-413 has unique ID: 414
| Nieduszynski et al. (2006): | A | T | G | T | T | T | T | T | T | G | T | T | T | T | G | T | ||||||||||||||||||||||||||
| Xu et al. (2006): | A | T | G | T | T | T | T | T | T | G | T | T | T | T | G | T | T | G | T | A | G | T | A | T | T | C | G | A | G | C | A | T | T | A | ||||||||
| Eaton et al. (2010): | A | T | G | T | T | T | T | T | T | G | T | T | T | T | G | T | T | G | T | A | G | T | A | T | T | C | G | A | G | C | A | T | T | |||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at XII-413 has unique ID: 414
| Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | A | C | A | A | A | A | T | T | A | A | A | A | A | C | T | G | T | T | T | A | A | T | G | T | T | T | T | T | T | G | T | T | T | T | G | T | T | G | T | A | G | T | A | T | T | C | G | A | G | C | A | T | T | A | A | G |
| S. kudriavzevii | G | C | A | A | A | A | C | T | A | A | A | A | A | T | C | G | A | T | T | A | A | T | - | - | T | T | A | T | T | T | T | T | T | G | G | T | - | - | C | G | A | T | A | T | T | C | T | T | C | C | A | T | T | T | T | G |
| S. paradoxus | G | C | A | A | A | A | C | T | A | G | A | A | A | T | C | G | T | T | C | A | T | T | G | T | T | T | T | T | T | G | T | T | T | T | G | T | T | C | C | A | A | T | A | T | T | T | A | A | G | A | A | T | T | A | G | G |
| S. bayanus | C | C | C | G | A | T | T | T | T | A | G | A | A | T | C | G | A | T | T | A | C | T | T | T | T | T | C | T | T | G | T | T | T | T | G | T | T | C | C | T | A | C | T | T | T | C | C | A | A | C | A | T | T | T | T | A |
| * | : | : | * | : | * | : | : | : | * | * | * | * | : | * | * | : | * | * | * | * | : | * | * | * | : | * | * | : | : | : | * | * | : | : | : | * | * | * | : | |||||||||||||||||
ARS at XII-413 has unique ID: 414
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at XII-413 has unique ID: 414
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at XII-413 has unique ID: 414
