Status: Confirmed ARS: Confirmed by ARS assay and identified by 11 genome-wide studies.
Genomic Location:
Chr11:516653-516902
Within tandem intergenic space between YKR039W and TA(AGC)K2.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -151.0 ΔG° (kcal/mol) at location 516833.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 26.2 min.
Yabuki et al. (2002) — Trep: 25.7 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at XI-517 has unique ID: 384
ARS at XI-517 has unique ID: 384
Chr11:516653-516902
None curated.
Chr11:516511-517093
Chr11:514910-517805
Chr11:515100-517200 (orc2-1/wt peak ratio: 0.84)
Chr11:516785-516795
Chr11:515450-517250 (orc1-bah-delta/wt peak ratio: 0.56)
Chr11:517400-517775
Chr11:516512 (Trep: 26.2 min.) (Confidence: 9)
Chr11:516002 (Trep: 25.7 min.)
Chr11:514870 (Peak first observed at 12.5 min.)
Chr11:515000 (Activity detected in: rad53)
Chr11:516653-516902 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at XI-517 has unique ID: 384
Nieduszynski et al. (2006): | T | T | T | T | T | T | T | A | C | T | T | T | T | T | G | T | ||||||||||||||||||||||||||
Xu et al. (2006): | T | T | A | C | T | T | T | T | T | G | T | T | A | T | T | T | T | A | T | T | T | A | T | G | T | T | T | T | T | C | T | A | G | G | ||||||||
Eaton et al. (2010): | T | T | T | T | T | T | T | A | C | T | T | T | T | T | G | T | T | A | T | T | T | T | A | T | T | T | A | T | G | T | T | T | T | |||||||||
ACS LOGO: |
ARS at XI-517 has unique ID: 384
Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S. cerevisiae | C | C | A | T | T | T | C | C | T | T | A | T | T | G | A | A | C | T | T | T | ||||||||||||||||||||||||||||||||||||
S. kudriavzevii | C | T | T | T | T | C | T | T | C | T | A | T | C | A | A | A | - | C | A | T | ||||||||||||||||||||||||||||||||||||
S. mikatae | C | C | C | T | T | C | T | C | T | T | A | T | T | A | A | A | A | C | T | T | ||||||||||||||||||||||||||||||||||||
S. paradoxus | C | T | C | C | T | T | A | C | T | T | A | T | T | T | A | A | C | C | T | T | ||||||||||||||||||||||||||||||||||||
S. bayanus | C | C | T | T | T | A | T | T | A | A | A | A | C | G | A | A | A | C | A | T | ||||||||||||||||||||||||||||||||||||
* | : | : | * | : | : | * | : | * | * | : | * |
ARS at XI-517 has unique ID: 384
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at XI-517 has unique ID: 384
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at XI-517 has unique ID: 384