Status: Confirmed ARS: Confirmed by ARS assay and identified by 11 genome-wide studies.
Genomic Location:
Chr10:683328-683817
Within divergent intergenic space between YJR137C and YJR138W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS confirmed.
Helical Stability: Minimum -144.0 ΔG° (kcal/mol) at location 683598.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 16.1 min.
Yabuki et al. (2002) — Trep: 18.3 min.
Alvino et al. (2007) — Peak first observed at 10.0 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at X-684 has unique ID: 354
ARS at X-684 has unique ID: 354
Chr10:683328-683817
None curated.
Chr10:682974-684256
Chr10:683165-684845
Chr10:683300-684600 (orc2-1/wt peak ratio: 1.00)
Chr10:683785-683795
Chr10:683225-684875 (orc1-bah-delta/wt peak ratio: 0.70)
Chr10:684266 (Trep: 16.1 min.) (Confidence: 9)
Chr10:682933 (Trep: 18.3 min.)
Chr10:684220 (Peak first observed at 10.0 min.)
Chr10:681000 (Activity detected in: rad53)
Chr10:685333
Chr10:683328-683817 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at X-684 has unique ID: 354
Nieduszynski et al. (2006): | T | T | G | T | T | T | A | A | C | A | T | T | A | G | T |
Xu et al. (2006): | T | T | T | T | G | T | G | A | G | A | A | A | A | T | A | T | A | T | T | T | T | G | G | A | T | G | A | A | T | A | G | C | A | G | ||||||||
Eaton et al. (2010): | T | T | T | G | T | T | T | A | A | C | A | T | T | A | G | T | T | T | C | A | A | A | T | T | A | A | C | A | G | C | T | T | T | |||||||||
ACS LOGO: |
ARS at X-684 has unique ID: 354
Confirmed ACS | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
S. cerevisiae | T | C | A | A | T | T | T | G | A | A | G | T | G | A | G | A | T | G | T | T | T | T | G | T | T | T | A | A | C | A | T | T | A | G | T | T | T | C | A | A | A | T | T | A | A | C | A | G | C | T | T | T | T | G | T |
S. kudriavzevii | T | T | A | A | G | G | G | G | A | A | A | C | A | G | T | A | T | G | A | G | G | T | A | T | T | T | A | A | T | A | T | T | T | T | T | T | T | C | C | C | A | A | T | T | T | T | A | T | C | T | T | T | T | C | T |
S. mikatae | C | C | A | A | G | A | T | T | G | A | G | C | A | G | A | A | T | G | C | T | T | T | A | T | T | T | A | A | T | A | T | T | T | G | T | T | T | C | C | A | A | A | T | G | A | C | A | G | C | T | T | T | C | A | T |
S. paradoxus | T | T | A | T | A | G | T | G | A | A | G | C | A | A | G | A | T | A | T | T | T | T | A | T | T | T | A | A | T | A | T | T | A | G | T | T | T | T | C | A | A | T | T | G | A | T | A | G | T | T | T | T | T | - | T |
S. bayanus | T | T | A | G | A | A | C | G | A | A | - | - | - | A | G | A | T | T | A | T | T | T | A | T | T | T | A | A | T | A | T | T | T | G | T | T | T | C | C | A | G | T | T | C | T | T | A | G | C | T | T | T | T | - | T |
: | * | : | : | : | : | * | : | : | * | * | : | : | * | : | * | * | * | * | * | : | * | * | * | : | * | * | * | : | : | : | : | * | : | * | : | : | * | * | * | : | : | * |
ARS at X-684 has unique ID: 354
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at X-684 has unique ID: 354
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at X-684 has unique ID: 354