Status: Confirmed ARS: Confirmed by ARS assay and identified by 10 genome-wide studies.
Genomic Location:
Chr8:447619-447853
Within tandem intergenic space between YHR171W and YHR172W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -137.3 ΔG° (kcal/mol) at location 447769.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 25.4 min.
Yabuki et al. (2002) — Trep: 20.9 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at VIII-448 has unique ID: 287
ARS at VIII-448 has unique ID: 287
Chr8:447619-447853
None curated.
Chr8:446595-447553
Chr8:446395-448355
Chr8:447000-448400 (orc2-1/wt peak ratio: 0.35)
Chr8:447805-447815
Chr8:446675-448550 (orc1-bah-delta/wt peak ratio: 0.39)
Chr8:447627 (Trep: 25.4 min.) (Confidence: 9)
Chr8:447835 (Trep: 20.9 min.)
Chr8:446780 (Peak first observed at 12.5 min.)
Chr8:446250 (Activity detected in: wild-type, rad53)
Chr8:447619-447853 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at VIII-448 has unique ID: 287
| Nieduszynski et al. (2006): | A | T | G | T | T | T | A | T | G | T | T | T | T | G | T | G | ||||||||||||||||||||||||||
| Xu et al. (2006): | T | T | A | T | G | T | T | T | A | T | G | T | T | T | T | G | T | G | A | G | T | A | A | A | G | T | C | A | A | G | A | A | T | T | ||||||||
| Eaton et al. (2010): | T | A | T | G | T | T | T | A | T | G | T | T | T | T | G | T | G | A | G | T | A | A | A | G | T | C | A | A | G | A | A | T | T | |||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at VIII-448 has unique ID: 287
| Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | T | G | A | G | G | A | C | T | T | T | A | T | T | A | C | A | T | T | T | T | A | T | G | T | T | T | A | T | G | T | T | T | T | G | T | G | A | G | T | A | A | A | G | T | C | A | A | G | A | A | T | T | T | G | T | C |
| S. kudriavzevii | T | A | A | G | A | G | C | T | T | A | T | T | G | A | - | G | T | T | G | T | A | T | A | T | T | T | A | T | G | T | T | T | T | G | A | T | G | C | C | A | G | A | G | T | G | A | A | C | A | A | A | C | T | T | T | C |
| S. mikatae | T | G | A | G | A | T | T | T | T | T | T | T | - | - | - | A | T | T | T | T | A | T | G | T | T | T | A | T | G | T | T | T | T | G | T | A | A | C | C | A | A | A | C | C | A | A | T | G | G | A | T | T | T | C | C | C |
| S. paradoxus | T | A | A | A | A | A | T | T | T | T | G | T | T | A | C | A | T | T | T | T | G | T | G | T | T | T | A | T | G | T | T | T | T | G | T | A | A | G | T | A | A | A | G | C | C | A | A | G | A | A | T | T | A | T | T | T |
| * | * | : | * | * | : | * | : | : | * | * | : | * | : | * | : | * | * | * | * | * | * | * | * | * | * | * | : | : | * | : | * | : | * | : | : | : | * | : | : | : | : | : | ||||||||||||||
ARS at VIII-448 has unique ID: 287
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at VIII-448 has unique ID: 287
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at VIII-448 has unique ID: 287
