Status: Confirmed ARS: Confirmed by ARS assay and identified by 10 genome-wide studies.
Genomic Location:
Chr8:64255-64489
Within tandem intergenic space between YHL022C and YHL021C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -141.1 ΔG° (kcal/mol) at location 64475.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 26.4 min.
Yabuki et al. (2002) — Trep: 24.9 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at VIII-64 has unique ID: 267
ARS at VIII-64 has unique ID: 267
Chr8:64255-64489
None curated.
Chr8:64154-64458
Chr8:62686-65393
Chr8:63600-65600 (orc2-1/wt peak ratio: 0.41)
Chr8:64135-64145
Chr8:63650-65150 (orc1-bah-delta/wt peak ratio: 0.46)
Chr8:65305 (Trep: 26.4 min.) (Confidence: 9)
Chr8:63335 (Trep: 24.9 min.)
Chr8:64750 (Peak first observed at 12.5 min.)
Chr8:63500 (Activity detected in: wild-type, rad53)
Chr8:64255-64489 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at VIII-64 has unique ID: 267
| Nieduszynski et al. (2006): | A | A | T | T | T | T | A | A | T | T | T | T | A | G | T | T | ||||||||||||||||||||||||||
| Xu et al. (2006): | T | A | T | A | T | T | T | A | T | T | T | T | A | A | G | A | A | G | C | C | G | T | C | A | G | T | T | T | C | C | T | T | T | T | ||||||||
| Eaton et al. (2010): | T | A | A | T | T | T | T | A | A | T | T | T | T | A | G | T | T | A | T | T | G | A | T | T | T | C | A | A | T | G | A | A | A | |||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at VIII-64 has unique ID: 267
| Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | T | T | T | T | A | C | G | T | T | A | T | T | C | C | T | T | T | T | A | T | A | A | T | T | T | T | A | A | T | T | T | T | A | G | T | T | A | T | T | G | A | T | T | T | C | A | A | T | G | A | A | A | C | A | A | A |
| S. kudriavzevii | T | T | G | A | A | T | G | T | T | G | T | T | T | C | C | T | T | T | A | T | T | T | T | T | T | T | A | G | T | T | T | T | A | G | T | C | A | A | T | G | G | T | G | C | T | G | G | T | G | C | A | - | - | G | A | A |
| S. mikatae | T | T | T | G | A | T | G | T | T | G | T | T | T | C | C | T | T | T | T | T | A | T | T | T | T | T | A | G | T | T | T | T | A | G | T | T | G | T | T | T | A | T | C | A | C | T | A | T | G | A | A | - | - | A | A | T |
| S. paradoxus | T | T | T | G | A | T | G | T | T | G | T | T | C | C | T | T | T | T | A | A | A | A | T | T | T | T | A | G | T | T | T | T | A | G | T | T | A | T | C | A | A | T | T | C | C | T | A | T | G | G | A | - | - | G | A | A |
| S. bayanus | A | T | T | G | A | C | G | T | T | A | T | T | T | A | T | C | T | T | A | A | A | A | G | T | T | T | A | G | T | T | T | T | A | G | T | T | A | T | G | G | T | T | T | T | G | T | A | A | G | A | A | - | - | A | A | C |
| : | * | : | : | * | * | * | * | * | * | : | : | * | * | : | : | : | * | * | * | * | : | * | * | * | * | * | * | * | : | : | : | * | : | : | : | * | * | : | : | * | ||||||||||||||||
ARS at VIII-64 has unique ID: 267
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at VIII-64 has unique ID: 267
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at VIII-64 has unique ID: 267
