Status: Confirmed ARS: Confirmed by ARS assay and identified by 10 genome-wide studies.
Genomic Location:
Chr4:1240869-1241098
Within tandem intergenic space between YDR383C and YDR384C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -144.4 ΔG° (kcal/mol) at location 1240959.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 36.7 min.
Yabuki et al. (2002) — Trep: 28.4 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at IV-1241 has unique ID: 146
ARS at IV-1241 has unique ID: 146
Chr4:1240869-1241098
None curated.
Chr4:1240752-1241238
Chr4:1239600-1241950
Chr4:1240300-1241800 (orc2-1/wt peak ratio: 0.55)
Chr4:1240995-1241005
Chr4:1240325-1241600 (orc1-bah-delta/wt peak ratio: 0.62)
Chr4:1243070 (Trep: 36.7 min.) (Confidence: 9)
Chr4:1243791 (Trep: 28.4 min.)
Chr4:1240000 (Peak first observed at 12.5 min.)
Chr4:1241000 (Activity detected in: rad53)
Chr4:1240869-1241098 (Activity detected in: mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at IV-1241 has unique ID: 146
| Nieduszynski et al. (2006): | T | T | G | A | T | T | T | A | T | A | T | T | T | A | G | T | ||||||||||||||||||||||||||
| Xu et al. (2006): | G | A | T | T | T | A | T | A | T | T | T | A | G | T | C | C | A | A | A | T | A | T | T | A | C | A | G | A | A | A | A | A | A | A | ||||||||
| Eaton et al. (2010): | T | T | G | A | T | T | T | A | T | A | T | T | T | A | G | T | C | C | A | A | A | T | A | T | T | A | C | A | G | A | A | A | A | |||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at IV-1241 has unique ID: 146
| Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | T | T | T | C | C | C | T | T | C | C | T | T | C | T | T | G | A | A | A | T | T | T | G | A | T | T | T | A | T | A | T | T | T | A | G | T | C | C | A | A | A | T | A | T | T | A | C | A | G | A | A | A | A | A | A | A |
| S. kudriavzevii | T | T | T | A | C | T | T | C | A | T | T | T | A | T | T | T | - | - | - | T | T | T | A | C | G | T | T | T | T | G | T | C | C | G | T | T | G | G | A | A | A | A | A | T | A | A | C | A | G | A | A | A | T | C | A | T |
| S. mikatae | T | T | T | C | C | A | T | T | C | C | T | T | A | T | T | A | A | G | T | T | T | T | G | T | T | T | T | T | T | A | T | T | T | A | G | T | C | C | A | A | A | G | T | T | T | G | A | A | G | G | A | C | T | A | A | G |
| S. paradoxus | T | T | C | C | C | T | T | T | C | C | C | T | C | T | - | - | - | - | - | T | T | T | A | T | T | T | T | A | T | G | T | T | T | A | G | T | T | C | A | A | C | T | A | C | T | A | C | A | G | A | A | A | A | T | A | A |
| S. bayanus | T | T | T | T | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | T | T | T | A | T | G | T | T | T | C | G | - | - | - | - | - | - | G | T | G | A | G | A | A | G | T | T | C | A | G | T | A | T | T | T | A | A |
| * | * | : | : | : | : | : | : | : | : | : | * | * | * | : | * | * | : | : | : | : | * | : | : | : | * | * | * | * | ||||||||||||||||||||||||||||
ARS at IV-1241 has unique ID: 146
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at IV-1241 has unique ID: 146
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at IV-1241 has unique ID: 146
