Status: Confirmed ARS: Confirmed by ARS assay and identified by 10 genome-wide studies.
Genomic Location:
Chr4:123617-123902
Within convergent intergenic space between YDL189W and YDL188C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -155.3 ΔG° (kcal/mol) at location 123877.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 29.4 min.
Yabuki et al. (2002) — Trep: 24.7 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at IV-124 has unique ID: 97
ARS at IV-124 has unique ID: 97
Chr4:123617-123902
None curated.
Chr4:123590-123866
Chr4:122895-124355
Chr4:123600-124500 (orc2-1/wt peak ratio: 0.41)
Chr4:123665-123675
Chr4:123650-124175 (orc1-bah-delta/wt peak ratio: 0.53)
Chr4:124282 (Trep: 29.4 min.) (Confidence: 9)
Chr4:126291 (Trep: 24.7 min.)
Chr4:124000 (Peak first observed at 12.5 min.)
Chr4:123000 (Activity detected in: rad53)
Chr4:123617-123902 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at IV-124 has unique ID: 97
Nieduszynski et al. (2006): | G | T | T | G | T | T | T | T | C | A | C | T | T | T | G | T | ||||||||||||||||||||||||||
Xu et al. (2006): | T | T | A | A | T | A | T | A | T | A | T | T | T | A | G | T | T | A | C | T | T | T | T | T | C | C | C | T | C | T | A | A | T | T | ||||||||
ACS LOGO: |
ARS at IV-124 has unique ID: 97
Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S. cerevisiae | A | C | A | G | T | A | A | T | A | T | A | T | G | A | G | A | A | A | A | A | G | T | T | G | T | T | T | T | C | A | C | T | T | T | G | T | G | T | T | C | G | A | A | A | A | A | A | T | A | A | G | T | A | T | T | T |
S. kudriavzevii | A | T | A | A | T | G | A | C | A | A | C | C | G | G | A | C | A | T | G | C | G | T | T | A | T | T | C | T | T | G | C | G | A | G | G | C | A | T | T | C | A | G | A | A | A | T | A | T | A | A | A | C | A | T | C | T |
S. mikatae | A | T | A | G | T | A | G | A | A | T | A | T | G | A | A | T | A | A | A | T | A | T | T | G | T | T | T | T | T | A | T | A | G | T | G | C | G | T | C | C | A | A | A | A | A | G | A | T | A | T | A | T | A | C | T | T |
S. paradoxus | A | C | A | G | T | A | A | T | A | T | T | T | G | A | G | T | A | A | A | A | G | T | T | G | T | A | T | T | C | A | C | A | A | T | G | C | G | T | T | C | G | G | G | A | A | G | A | T | G | A | G | T | A | T | T | T |
S. bayanus | G | T | G | T | T | G | A | A | T | A | T | C | A | G | G | C | A | A | A | A | T | T | G | G | T | T | T | T | G | A | T | A | A | T | G | C | A | T | T | T | G | G | G | T | A | A | A | T | A | T | A | T | A | T | - | - |
: | : | * | : | : | : | : | * | : | : | * | : | : | * | : | : | * | : | : | : | : | * | : | * | : | : | : | * | * | * | : | : | * | : | : |
ARS at IV-124 has unique ID: 97
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at IV-124 has unique ID: 97
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
ARS at IV-124 has unique ID: 97