OriDB - ARS at XVI-262

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Status: Likely ARS: Identified by 10 genome-wide studies.

Genomic Location: Chr16:261168-262687
Probably within tandem intergenic space between YPL154C and YPL153C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -158.2 ΔG° (kcal/mol) at location 261268.

Time of Origin Replication (Trep): Raghuraman et al. (2001) — Trep: 28.7 min.
Yabuki et al. (2002) — Trep: 27.2 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at XVI-262 has unique ID: 604

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ARS at XVI-262 has unique ID: 604

Studies that cloned this origin

None curated.

Studies that analyzed this origin by 2D gel

None curated.

Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Wyrick et al. (2001): Chr16:260930-261726

Xu et al. (2006): Chr16:261170-262685

Shor et al. (2009): Chr16:259700-260700 (orc2-1/wt peak ratio: 0.99)

Szilard et al. (2010): Chr16:261525-261535

MÃ¼ller et al. (2010): Chr16:261275-261875 (orc1-bah-delta/wt peak ratio: 0.39)

Studies that measured the replication time of this origin

Raghuraman et al. (2001): Chr16:253877 (Trep: 28.7 min.) (Confidence: 3)

Yabuki et al. (2002): Chr16:261633 (Trep: 27.2 min.)

Alvino et al. (2007): Chr16:261000 (Peak first observed at 12.5 min.)

Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr16:260666 (Activity detected in: rad53)

CrabbÃ© et al. (2010): Chr16:261168-262687 (Activity detected in: tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)