Status: Confirmed ARS: Confirmed by ARS assay and 2D gel and identified by 10 genome-wide studies.
Genomic Location:
Chr14:279875-280108
Within tandem intergenic space between YNL192W and YNL191W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -147.2 ΔG° (kcal/mol) at location 280075.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 24.7 min.
Yabuki et al. (2002) — Trep: 25.9 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at XIV-280 has unique ID: 515
ARS at XIV-280 has unique ID: 515
Chr14:279875-280108
Chr14:277746-281725
Chr14:279893-280428
Chr14:279285-281255
Chr14:279300-280700 (orc2-1/wt peak ratio: 0.79)
Chr14:280015-280025
Chr14:279350-280700 (orc1-bah-delta/wt peak ratio: 0.51)
Chr14:279803 (Trep: 24.7 min.) (Confidence: 9)
Chr14:282469 (Trep: 25.9 min.)
Chr14:281000 (Peak first observed at 12.5 min.)
Chr14:279666 (Activity detected in: rad53)
Chr14:279875-280108 (Activity detected in: ddc1, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at XIV-280 has unique ID: 515
Nieduszynski et al. (2006): | T | T | A | T | T | T | A | T | G | T | T | T | T | T | C | T | ||||||||||||||||||||||||||
Xu et al. (2006): | T | C | A | A | T | T | A | T | T | T | A | T | G | T | T | T | T | T | C | T | C | T | C | A | G | A | A | G | C | C | A | T | T | T | ||||||||
ACS LOGO: | ![]() |
ARS at XIV-280 has unique ID: 515
Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
* |
ARS at XIV-280 has unique ID: 515
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at XIV-280 has unique ID: 515
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
ARS at XIV-280 has unique ID: 515