Status: Confirmed ARS: Confirmed by ARS assay and identified by 9 genome-wide studies.
Genomic Location:
Chr4:1404277-1404512
Within convergent intergenic space between YDR472W and YDR473C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -145.1 ΔG° (kcal/mol) at location 1404397.
Time of Origin Replication (Trep):
Yabuki et al. (2002) — Trep: 30.0 min.
Alvino et al. (2007) — Peak first observed at 17.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at IV-1404 has unique ID: 156
ARS at IV-1404 has unique ID: 156
Chr4:1404277-1404512
None curated.
Chr4:1404207-1404479
Chr4:1403250-1405400
Chr4:1403600-1405000 (orc2-1/wt peak ratio: 0.45)
Chr4:1404375-1404385
Chr4:1403600-1405325 (orc1-bah-delta/wt peak ratio: 0.67)
Chr4:1406791 (Trep: 30.0 min.)
Chr4:1402800 (Peak first observed at 17.5 min.)
Chr4:1403666 (Activity detected in: rad53)
Chr4:1404277-1404512 (Activity detected in: ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at IV-1404 has unique ID: 156
Nieduszynski et al. (2006): | T | C | T | T | T | T | T | A | T | A | T | T | T | T | G | G | ||||||||||||||||||||||||||
Xu et al. (2006): | T | T | T | T | T | A | T | A | T | T | T | T | G | G | A | A | T | G | T | T | T | T | T | G | T | G | C | T | A | A | A | A | A | A | ||||||||
Eaton et al. (2010): | T | C | T | T | T | T | T | A | T | A | T | T | T | T | G | G | A | A | T | G | T | T | T | T | T | G | T | G | C | T | A | A | A | |||||||||
ACS LOGO: |
ARS at IV-1404 has unique ID: 156
Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S. cerevisiae | T | C | T | A | T | C | A | T | A | T | A | A | A | A | T | C | A | T | T | T | T | C | T | T | T | T | T | A | T | A | T | T | T | T | G | G | A | A | T | G | T | T | T | T | T | G | T | G | C | T | A | A | A | A | A | A |
S. kudriavzevii | G | C | T | A | T | G | A | A | A | T | A | T | T | A | T | G | A | T | A | T | - | - | - | A | T | T | T | A | A | G | T | T | T | G | G | G | T | A | A | T | A | A | T | T | C | T | T | G | T | C | A | A | A | A | A | A |
S. mikatae | A | C | T | A | C | A | G | T | T | T | A | C | G | A | C | C | A | T | A | T | T | - | - | T | T | T | T | A | T | A | T | T | T | A | G | A | G | A | C | A | A | G | T | T | G | G | T | G | C | T | G | T | G | A | A | A |
S. paradoxus | T | T | T | G | C | A | A | T | G | T | A | G | C | C | C | C | A | T | T | T | T | T | T | T | T | T | T | A | T | G | T | T | T | T | G | G | A | A | C | A | T | T | T | T | C | G | T | A | C | T | A | A | G | A | A | G |
S. bayanus | T | C | T | A | T | G | G | - | A | T | A | A | T | A | C | C | G | G | A | G | T | T | T | T | T | T | T | A | A | G | T | T | T | A | G | G | T | A | T | T | A | T | T | T | C | G | T | G | A | C | A | A | A | G | A | A |
: | * | : | : | * | * | : | : | : | : | : | : | : | : | : | * | * | * | * | * | * | * | * | : | * | : | * | * | : | : | * | : | : | : | : | * | : |
ARS at IV-1404 has unique ID: 156
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at IV-1404 has unique ID: 156
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at IV-1404 has unique ID: 156