Status: Confirmed ARS: Confirmed by ARS assay and 2D gel and identified by 9 genome-wide studies.
Genomic Location:
Chr4:408070-408312
Within tandem intergenic space between YDL025C and YDL024C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -151.3 ΔG° (kcal/mol) at location 408280.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 26.3 min.
Yabuki et al. (2002) — Trep: 21.8 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at IV-408 has unique ID: 108
ARS at IV-408 has unique ID: 108
Chr4:408070-408312
Chr4:404295-409192
Chr4:407247-408492
Chr4:407505-409225
Chr4:408275-408285
Chr4:407825-408350 (orc1-bah-delta/wt peak ratio: 0.40)
Chr4:409855 (Trep: 26.3 min.) (Confidence: 5)
Chr4:406291 (Trep: 21.8 min.)
Chr4:407250 (Peak first observed at 12.5 min.)
Chr4:407750 (Activity detected in: wild-type, rad53)
Chr4:408070-408312 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at IV-408 has unique ID: 108
| Nieduszynski et al. (2006): | T | A | T | A | T | T | A | T | A | T | T | T | A | G | C | G | ||||||||||||||||||||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at IV-408 has unique ID: 108
| Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | G | A | A | T | A | G | C | C | G | T | T | C | A | T | C | T | C | T | T | T | T | A | T | A | T | T | A | T | A | T | T | T | A | G | C | G | A | T | G | T | A | A | T | G | A | A | A | G | T | A | A | A | A | A | A | A |
| S. kudriavzevii | A | A | A | A | T | G | C | C | T | A | T | T | A | T | G | T | T | C | G | G | A | A | T | A | T | T | A | T | G | T | T | T | A | G | T | A | A | T | A | T | A | A | C | G | T | G | T | G | C | A | A | A | A | G | G | A |
| S. mikatae | G | A | A | A | A | A | T | A | T | T | T | C | A | C | C | T | T | C | G | C | A | A | T | A | T | T | A | T | A | T | T | T | A | G | T | T | A | C | T | T | A | A | T | T | T | A | G | G | T | A | A | A | A | A | A | A |
| S. paradoxus | G | A | A | A | A | G | C | G | T | T | T | C | A | T | T | T | C | G | G | C | - | A | T | A | T | T | A | T | A | T | T | T | A | G | T | T | A | T | G | T | A | A | T | A | T | A | A | G | T | A | A | A | T | A | A | A |
| : | * | * | : | : | : | : | * | : | * | : | * | * | * | * | * | * | * | * | : | * | * | * | * | * | * | : | * | * | * | : | : | * | : | * | * | * | : | : | : | * | ||||||||||||||||
ARS at IV-408 has unique ID: 108
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at IV-408 has unique ID: 108
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
None identified.
PubMed | PubMed Central | Genes Dev.
ARS at IV-408 has unique ID: 108
