OriDB - ARS at XII-618

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Status: Dubious ARS: Identified by 9 genome-wide studies.

Genomic Location: Chr12:612500-622500
Resolution insufficient to assign intergenic space.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -160.7 ΔG° (kcal/mol) at location 613410.

Time of Origin Replication (Trep): Raghuraman et al. (2001) — Trep: 20.0 min.
Yabuki et al. (2002) — Trep: 24.4 min.
Alvino et al. (2007) — Peak first observed at 25.0 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at XII-618 has unique ID: 874

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ARS at XII-618 has unique ID: 874

Studies that cloned this origin

None curated.

Studies that analyzed this origin by 2D gel

None curated.

Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Xu et al. (2006): Chr12:622105-623935

Shor et al. (2009): Chr12:622600-623100 (orc2-1/wt peak ratio: 0.00)

Szilard et al. (2010): Chr12:622975-622985

MÃ¼ller et al. (2010): Chr12:622400-623150 (orc1-bah-delta/wt peak ratio: 0.57)

Studies that measured the replication time of this origin

Raghuraman et al. (2001): Chr12:606519 (Trep: 20.0 min.) (Confidence: 9)

Yabuki et al. (2002): Chr12:619804 (Trep: 24.4 min.)

Alvino et al. (2007): Chr12:617500 (Peak first observed at 25.0 min.)

Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr12:623000 (Activity detected in: rad53)

CrabbÃ© et al. (2010): Chr12:622946-623446 (Activity detected in: wild-type, rev3 rad30, eco1, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)