Status: Confirmed ARS: Confirmed by ARS assay and identified by 7 genome-wide studies.
Genomic Location:
Chr14:545966-546201
Within tandem intergenic space between YNL044W and TP(UGG)N1.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -144.9 ΔG° (kcal/mol) at location 546196.
Time of Origin Replication (Trep): This site was not identified as an origin by any curated timing study (Raghuraman et al. (2001); Yabuki et al. (2002); Alvino et al. (2007)), suggesting that this site is not chromosomally active for replication initiation.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at XIV-546 has unique ID: 526
ARS at XIV-546 has unique ID: 526
Chr14:545966-546201
None curated.
Chr14:545907-546421
Chr14:545535-547415
Chr14:545600-546700 (orc2-1/wt peak ratio: 0.34)
Chr14:546185-546195
Chr14:545675-546875 (orc1-bah-delta/wt peak ratio: 0.69)
The replication time of origin has not be reported by any curated study.
Chr14:545500 (Activity detected in: rad53)
Chr14:545966-546201 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at XIV-546 has unique ID: 526
| Nieduszynski et al. (2006): | A | T | T | T | T | T | A | C | G | T | T | T | T | G | G | C | ||||||||||||||||||||||||||
| Xu et al. (2006): | T | A | T | T | A | T | T | T | T | T | A | C | G | T | T | T | T | G | G | C | A | C | G | T | G | A | A | T | C | T | T | C | A | G | ||||||||
| Xu et al. (2006): | G | T | T | T | A | T | G | T | T | T | T | T | T | T | C | G | T | T | T | A | T | C | A | A | G | C | G | T | G | C | A | A | T | C | ||||||||
| Eaton et al. (2010): | T | A | T | T | T | T | T | A | C | G | T | T | T | T | G | G | C | A | C | G | T | G | A | A | T | C | T | T | C | A | G | T | A | |||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at XIV-546 has unique ID: 526
| Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | - | - | - | - | - | - | G | T | T | A | T | G | T | T | A | T | T | A | T | T | A | T | T | T | T | T | A | C | G | T | T | T | T | G | G | C | A | C | G | T | G | A | A | T | C | T | T | C | A | G | T | A | A | T | T | G |
| S. kudriavzevii | - | - | - | - | - | - | T | T | A | A | T | G | T | T | A | T | G | A | T | T | - | G | T | T | T | T | A | C | G | T | T | T | A | G | G | C | A | G | G | T | G | G | A | G | C | T | A | A | T | A | T | T | A | T | T | A |
| S. mikatae | - | - | - | - | - | - | G | T | A | G | T | G | T | T | T | T | C | A | C | T | T | T | T | T | T | T | A | C | G | T | T | T | A | G | G | C | C | T | T | T | C | A | T | A | C | T | T | G | A | T | G | T | A | T | T | T |
| S. paradoxus | - | - | - | - | - | - | G | T | T | A | T | G | T | T | A | T | T | A | T | T | T | T | T | T | T | T | A | C | C | T | T | T | A | G | G | C | A | C | G | T | G | A | A | T | C | T | T | A | A | A | T | G | A | T | T | A |
| : | * | : | * | * | * | * | : | * | * | : | * | : | * | * | * | * | * | * | : | * | * | * | * | * | * | : | : | * | : | : | : | * | * | : | : | : | * | * | * | |||||||||||||||||
ARS at XIV-546 has unique ID: 526
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at XIV-546 has unique ID: 526
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | Genes Dev.
ARS at XIV-546 has unique ID: 526
