Status: Confirmed ARS: Confirmed by ARS assay and identified by 8 genome-wide studies.
Genomic Location:
Chr12:1007180-1007470
Within convergent intergenic space between YLR435W and YLR436C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -134.4 ΔG° (kcal/mol) at location 1007180.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 27.8 min.
Yabuki et al. (2002) — Trep: 27.1 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at XII-1007 has unique ID: 444
ARS at XII-1007 has unique ID: 444
Chr12:1007180-1007470
None curated.
Chr12:1006989-1007415
Chr12:1007265-1007275
Chr12:1007075-1007525 (orc1-bah-delta/wt peak ratio: 0.46)
Chr12:1006700 (Trep: 27.8 min.) (Confidence: 9)
Chr12:1006804 (Trep: 27.1 min.)
Chr12:1008100 (Peak first observed at 12.5 min.)
Chr12:1006666 (Activity detected in: rad53)
Chr12:1007180-1007470 (Activity detected in: wild-type, rev3 rad30, eco1, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at XII-1007 has unique ID: 444
| Nieduszynski et al. (2006): | T | A | T | T | T | T | T | A | T | A | T | T | T | T | G | T | ||||||||||||||||||||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at XII-1007 has unique ID: 444
| Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | T | G | T | G | T | A | T | T | T | T | T | T | A | T | G | T | T | T | C | A | T | A | T | T | T | T | T | A | T | A | T | T | T | T | G | T | G | T | T | T | G | C | T | A | A | G | G | T | C | T | A | A | T | C | G | T |
| S. kudriavzevii | G | A | G | A | T | G | A | A | T | T | A | C | G | T | A | T | T | C | C | C | C | A | A | T | T | T | T | G | T | A | T | T | T | G | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| S. mikatae | T | - | - | - | C | A | T | G | C | T | T | C | A | T | C | C | G | G | A | A | T | A | T | T | T | T | T | A | T | G | T | T | T | T | C | T | T | A | T | A | A | C | T | G | G | G | G | A | A | A | A | T | T | T | G | T |
| S. paradoxus | G | A | A | A | T | G | A | T | C | T | T | T | A | T | G | C | T | T | G | A | T | A | T | T | T | T | T | A | T | A | T | T | T | T | G | T | A | A | T | T | A | T | A | G | A | G | G | A | C | T | A | C | T | T | G | T |
| S. bayanus | T | A | T | A | T | A | A | T | T | T | T | T | G | T | C | A | T | G | A | T | T | C | A | C | T | T | T | A | C | A | T | A | C | T | G | G | A | C | G | A | G | - | - | - | - | - | - | T | A | A | A | A | C | T | G | T |
| : | : | : | * | : | * | : | : | : | : | * | * | * | : | : | : | * | : | : | : | : | : | : | : | : | : | : | ||||||||||||||||||||||||||||||
ARS at XII-1007 has unique ID: 444
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at XII-1007 has unique ID: 444
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | Mol. Cell. Biol.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
ARS at XII-1007 has unique ID: 444
