ARS1117

Status: Confirmed ARS: Confirmed by ARS assay and identified by 7 genome-wide studies.

Genomic Location: Chr11:530070-530560
Within tandem intergenic space between YKR050W and YKR051W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence: View sequence

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -150.5 ΔG° (kcal/mol) at location 530460.

Time of Origin Replication (Trep): Raghuraman et al. (2001) — Trep: 29.9 min.
Yabuki et al. (2002) — Trep: 27.1 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at XI-530 has unique ID: 385

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ARS at XI-530 has unique ID: 385

Studies that cloned this origin

Müller & Nieduszynski (2012): Chr11:530070-530560

Studies that analyzed this origin by 2D gel

None curated.

Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Wyrick et al. (2001): Chr11:530124-530586

Xu et al. (2006): Chr11:528845-531475

Szilard et al. (2010): Chr11:530265-530275

Studies that measured the replication time of this origin

Raghuraman et al. (2001): Chr11:533020 (Trep: 29.9 min.) (Confidence: 3)

Yabuki et al. (2002): Chr11:530002 (Trep: 27.1 min.)

Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr11:530000 (Activity detected in: rad53)

Crabbé et al. (2010): Chr11:529750-530250 (Activity detected in: ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)

Studies that predicted the location of this origin

This origin has not been predicted by any curated study.

ARS at XI-530 has unique ID: 385

Studies that confirmed an essential ACS element

None curated.

Studies that predicted an essential ACS element

None curated.

ACS LOGO:

ARS at XI-530 has unique ID: 385

Alignments from the UCSC genome browser

ARS at XI-530 has unique ID: 385

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at XI-530 has unique ID: 385

Genome-wide studies that identified this origin

Raghuraman et al. (2001): PubMed | Science

Wyrick et al. (2001): PubMed | Science

Yabuki et al. (2002): PubMed

Feng et al. (2006): PubMed | PubMed Central | Nat. Cell Biol.

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Szilard et al. (2010): PubMed | PubMed Central | Nat. Struct. Mol. Biol.

Crabbé et al. (2010): PubMed | Nat. Struct. Mol. Biol.

Studies that cloned this origin

Müller & Nieduszynski (2012): PubMed | Genome Res.

Studies that analyzed this origin by 2D gel

None identified.

Studies that confirmed an essential ACS element

None identified.

Studies that predicted an essential ACS element

None identified.

ARS at XI-530 has unique ID: 385