Likely ARS at IX-249

No systematic name assigned

Other names: proARS915

Status: Likely ARS: Identified by 11 genome-wide studies.

Genomic Location: Chr9:247893-249347
Resolution insufficient to assign intergenic space.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -174.5 ΔG° (kcal/mol) at location 249243.

Time of Origin Replication (Trep): Yabuki et al. (2002) — Trep: 24.3 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at IX-249 has unique ID: 315

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ARS at IX-249 has unique ID: 315

Studies that cloned this origin

None curated.


Studies that analyzed this origin by 2D gel

None curated.


Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Wyrick et al. (2001): Chr9:247195-247899

Wyrick et al. (2001): Chr9:248393-248847

Xu et al. (2006): Chr9:244105-249175

Shor et al. (2009): Chr9:244800-249100 (orc2-1/wt peak ratio: 0.76)

Szilard et al. (2010): Chr9:247805-247815

Müller et al. (2010): Chr9:244550-248975 (orc1-bah-delta/wt peak ratio: 0.75)

Müller et al. (2010): Chr9:244550-248975


Studies that measured the replication time of this origin

Yabuki et al. (2002): Chr9:249591 (Trep: 24.3 min.)

Alvino et al. (2007): Chr9:247750 (Peak first observed at 12.5 min.)


Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr9:246750 (Activity detected in: wild-type, rad53)

Crabbé et al. (2010): Chr9:247579-247800 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)


Studies that predicted the location of this origin

This origin has not been predicted by any curated study.



ARS at IX-249 has unique ID: 315

Studies that confirmed an essential ACS element

None curated.


Studies that predicted an essential ACS element

None curated.

ACS LOGO:   ACS_logo  


ARS at IX-249 has unique ID: 315

Alignments from the UCSC genome browser

No phylogenetic sequence conservation data.

ARS at IX-249 has unique ID: 315

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at IX-249 has unique ID: 315

Genome-wide studies that identified this origin

Wyrick et al. (2001): PubMed | Science

Yabuki et al. (2002): PubMed

Feng et al. (2006): PubMed | PubMed Central | Nat. Cell Biol.

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Shor et al. (2009): PubMed | PubMed Central | PLoS Genet.

Szilard et al. (2010): PubMed | PubMed Central | Nat. Struct. Mol. Biol.

Müller et al. (2010): PubMed | PubMed Central | Genes Dev.

Crabbé et al. (2010): PubMed | Nat. Struct. Mol. Biol.


Studies that cloned this origin

None identified.


Studies that analyzed this origin by 2D gel

None identified.


Studies that confirmed an essential ACS element

None identified.


Studies that predicted an essential ACS element

None identified.


ARS at IX-249 has unique ID: 315