Likely ARS at IX-407

No systematic name assigned

Status: Likely ARS: Identified by 8 genome-wide studies.

Genomic Location: Chr9:405633-407617
Probably within tandem intergenic space between YIR026C and YIR027C.
View at UCSC genome browser
View on SGD Chromosome Features Map
View at SGD gbrowser site
View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -166.0 ΔG° (kcal/mol) at location 407173.

Time of Origin Replication (Trep): Raghuraman et al. (2001) — Trep: 20.4 min.
Yabuki et al. (2002) — Trep: 20.9 min.
Alvino et al. (2007) — Peak first observed at 10.0 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at IX-407 has unique ID: 707

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ARS at IX-407 has unique ID: 707

Studies that cloned this origin

None curated.


Studies that analyzed this origin by 2D gel

None curated.


Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Xu et al. (2006): Chr9:405635-407615

Shor et al. (2009): Chr9:406200-407500 (orc2-1/wt peak ratio: 0.24)

Müller et al. (2010): Chr9:406175-406775 (orc1-bah-delta/wt peak ratio: 0.21)


Studies that measured the replication time of this origin

Raghuraman et al. (2001): Chr9:411264 (Trep: 20.4 min.) (Confidence: 9)

Yabuki et al. (2002): Chr9:411591 (Trep: 20.9 min.)

Alvino et al. (2007): Chr9:412670 (Peak first observed at 10.0 min.)


Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr9:411333 (Activity detected in: wild-type, rad53)

Crabbé et al. (2010): Chr9:406042-406542 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)


Studies that predicted the location of this origin

This origin has not been predicted by any curated study.



ARS at IX-407 has unique ID: 707

Studies that confirmed an essential ACS element

None curated.


Studies that predicted an essential ACS element

None curated.

ACS LOGO:   ACS_logo  


ARS at IX-407 has unique ID: 707

Alignments from the UCSC genome browser

No phylogenetic sequence conservation data.

ARS at IX-407 has unique ID: 707

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at IX-407 has unique ID: 707

Genome-wide studies that identified this origin

Raghuraman et al. (2001): PubMed | Science

Yabuki et al. (2002): PubMed

Feng et al. (2006): PubMed | PubMed Central | Nat. Cell Biol.

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Shor et al. (2009): PubMed | PubMed Central | PLoS Genet.

Müller et al. (2010): PubMed | PubMed Central | Genes Dev.

Crabbé et al. (2010): PubMed | Nat. Struct. Mol. Biol.


Studies that cloned this origin

None identified.


Studies that analyzed this origin by 2D gel

None identified.


Studies that confirmed an essential ACS element

None identified.


Studies that predicted an essential ACS element

None identified.


ARS at IX-407 has unique ID: 707