ARS213

Status: Confirmed ARS: Confirmed by ARS assay and identified by 7 genome-wide studies.

Genomic Location: Chr2:389245-390368
Within tandem intergenic space between YBR074W and YBR076W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence: View sequence

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -150.1 ΔG° (kcal/mol) at location 389335.

Time of Origin Replication (Trep): Alvino et al. (2007) — Peak first observed at 12.5 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at II-390 has unique ID: 40

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ARS at II-390 has unique ID: 40

Studies that cloned this origin

Xu et al. (2006): Chr2:389245-390368

Studies that analyzed this origin by 2D gel

None curated.

Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Wyrick et al. (2001): Chr2:389171-390329

Xu et al. (2006): Chr2:388255-390305

Szilard et al. (2010): Chr2:389375-389385

Müller et al. (2010): Chr2:389225-389900 (orc1-bah-delta/wt peak ratio: 0.23)

Studies that measured the replication time of this origin

Alvino et al. (2007): Chr2:382330 (Peak first observed at 12.5 min.)

Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr2:388666 (Activity detected in: rad53)

Crabbé et al. (2010): Chr2:389245-390368 (Activity detected in: tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)

Studies that predicted the location of this origin

This origin has not been predicted by any curated study.

ARS at II-390 has unique ID: 40

Studies that confirmed an essential ACS element

None curated.

Studies that predicted an essential ACS element

None curated.

ACS LOGO:

ARS at II-390 has unique ID: 40

Alignments from the UCSC genome browser

ARS at II-390 has unique ID: 40

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at II-390 has unique ID: 40

Genome-wide studies that identified this origin

Wyrick et al. (2001): PubMed | Science

Feng et al. (2006): PubMed | PubMed Central | Nat. Cell Biol.

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Szilard et al. (2010): PubMed | PubMed Central | Nat. Struct. Mol. Biol.

Müller et al. (2010): PubMed | PubMed Central | Genes Dev.

Crabbé et al. (2010): PubMed | Nat. Struct. Mol. Biol.

Studies that cloned this origin

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Studies that analyzed this origin by 2D gel

None identified.

Studies that confirmed an essential ACS element

None identified.

Studies that predicted an essential ACS element

None identified.

ARS at II-390 has unique ID: 40