Status: Confirmed ARS: Confirmed by ARS assay and identified by 7 genome-wide studies.
Genomic Location:
Chr4:567490-567737
Within convergent intergenic space between YDR057W and YDR058C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS predicted.
Helical Stability: Minimum -145.0 ΔG° (kcal/mol) at location 567700.
Time of Origin Replication (Trep): This site was not identified as an origin by any curated timing study (Raghuraman et al. (2001); Yabuki et al. (2002); Alvino et al. (2007)), suggesting that this site is not chromosomally active for replication initiation.
Origin activity in HU: Origin activity detected in HU — more details.
ARS at IV-568 has unique ID: 115
ARS at IV-568 has unique ID: 115
Chr4:567490-567737
None curated.
Chr4:567729-568649
Chr4:566955-569185
Chr4:567300-568100 (orc2-1/wt peak ratio: 0.31)
Chr4:567685-567695
Chr4:567425-568025 (orc1-bah-delta/wt peak ratio: 0.28)
The replication time of origin has not be reported by any curated study.
Chr4:568000 (Activity detected in: rad53)
Chr4:567490-567737 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)
This origin has not been predicted by any curated study.
ARS at IV-568 has unique ID: 115
Nieduszynski et al. (2006): | T | T | T | T | T | T | A | T | G | T | T | T | T | G | A | G | ||||||||||||||||||||||||||
Xu et al. (2006): | T | T | T | T | T | T | T | T | T | A | T | G | T | T | T | T | G | A | G | C | C | T | A | C | A | C | C | T | G | T | T | G | G | T | ||||||||
Xu et al. (2006): | T | T | T | T | C | A | C | G | T | T | T | T | G | C | C | T | T | T | T | A | T | A | T | A | C | C | G | A | T | T | A | A | A | T | ||||||||
ACS LOGO: |
ARS at IV-568 has unique ID: 115
Predicted ACS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S. cerevisiae | C | T | G | T | T | T | A | T | A | G | A | A | T | A | C | T | C | T | T | T | T | T | T | T | T | T | A | T | G | T | T | T | T | G | A | G | C | C | T | A | C | A | C | C | T | G | T | T | G | G | T | G | T | C | G | G |
S. mikatae | C | T | T | T | A | T | G | T | A | A | A | G | T | A | C | C | T | T | T | T | T | T | T | - | - | - | - | - | - | - | - | - | - | A | A | G | T | T | T | A | T | G | C | A | T | A | T | A | T | T | T | A | T | T | G | A |
S. paradoxus | C | T | G | T | A | C | A | G | A | A | T | A | T | C | T | C | T | C | C | T | T | T | T | T | T | T | A | T | G | T | T | T | T | G | A | T | C | T | C | A | A | A | T | T | T | A | C | T | G | A | C | G | T | T | G | G |
S. bayanus | G | T | G | T | A | T | G | C | A | A | A | T | T | A | T | T | G | T | C | T | T | T | T | T | T | T | A | A | G | T | T | T | T | G | T | A | T | A | T | A | C | T | T | T | T | A | C | T | T | A | C | G | T | T | G | T |
: | * | : | * | : | * | : | * | : | : | * | * | * | * | : | : | : | : | : | : | : | : | : | : | : | : | * | * | : | : | * | * |
ARS at IV-568 has unique ID: 115
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at IV-568 has unique ID: 115
PubMed | PubMed Central | Nat. Cell Biol.
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
None identified.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
ARS at IV-568 has unique ID: 115