OriDB Curated Paper

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Prediction of Saccharomyces cerevisiae replication origins.

Adam M Breier, Sourav Chatterji, Nicholas R Cozzarelli

Genome Biol. (2004), 5(4):R22PubMed | PubMed Central | Genome Biol.

Autonomously replicating sequences (ARSs) function as replication origins in Saccharomyces cerevisiae. ARSs contain the 17 bp ARS consensus sequence (ACS), which binds the origin recognition complex. The yeast genome contains more than 10,000 ACS matches, but there are only a few hundred origins, and little flanking sequence similarity has been found. Thus, identification of origins by sequence alone has not been possible.

OriDB annotation of this paper:

ARS assay

ARS824, ARS911.5, ARS912, ARS1331.5, ARS1509.5, ARS1514, ARS1529.5

2D gel

None curated.

ChIP of replication origin proteins

None curated.

Replication timing

None curated.

Replication in hydroxyurea

None curated.

Predicted origins

None curated.

Confirmed sequence element


Predicted sequence element

None curated.

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