Confirmed ARS at XII-93

ARS1206.5

Status: Confirmed ARS: Confirmed by ARS assay and identified by 6 genome-wide studies.

Genomic Location: Chr12:93166-93659
Within tandem intergenic space between TP(UGG)L and YLL025W.
View at UCSC genome browser
View on SGD Chromosome Features Map
View at SGD gbrowser site
View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -152.5 ΔG° (kcal/mol) at location 93406.

Time of Origin Replication (Trep): Raghuraman et al. (2001) — Trep: 27.6 min.
Yabuki et al. (2002) — Trep: 24.2 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at XII-93 has unique ID: 807

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ARS at XII-93 has unique ID: 807

Studies that cloned this origin

Müller & Nieduszynski (2012): Chr12:93166-93659


Studies that analyzed this origin by 2D gel

None curated.


Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Xu et al. (2006): Chr12:90126-97329

Szilard et al. (2010): Chr12:93605-93615


Studies that measured the replication time of this origin

Raghuraman et al. (2001): Chr12:94291 (Trep: 27.6 min.) (Confidence: 9)

Yabuki et al. (2002): Chr12:90804 (Trep: 24.2 min.)

Alvino et al. (2007): Chr12:88875 (Peak first observed at 12.5 min.)


Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr12:91750 (Activity detected in: wild-type, rad53)


Studies that predicted the location of this origin

This origin has not been predicted by any curated study.



ARS at XII-93 has unique ID: 807

Studies that confirmed an essential ACS element

None curated.


Studies that predicted an essential ACS element

None curated.

ACS LOGO:   ACS_logo  


ARS at XII-93 has unique ID: 807

Alignments from the UCSC genome browser

No phylogenetic sequence conservation data.

ARS at XII-93 has unique ID: 807

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at XII-93 has unique ID: 807

Genome-wide studies that identified this origin

Raghuraman et al. (2001): PubMed | Science

Yabuki et al. (2002): PubMed

Feng et al. (2006): PubMed | PubMed Central | Nat. Cell Biol.

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Szilard et al. (2010): PubMed | PubMed Central | Nat. Struct. Mol. Biol.


Studies that cloned this origin

Müller & Nieduszynski (2012): PubMed | Genome Res.


Studies that analyzed this origin by 2D gel

None identified.


Studies that confirmed an essential ACS element

None identified.


Studies that predicted an essential ACS element

None identified.


ARS at XII-93 has unique ID: 807