Dubious ARS at XII-786

No systematic name assigned

Status: Dubious ARS: Identified by 5 genome-wide studies.

Genomic Location: Chr12:785588-786917
Probably within tandem intergenic space between YLR328W and YLR329W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: ACS predicted.

Helical Stability: Minimum -156.4 ΔG° (kcal/mol) at location 785768.

Time of Origin Replication (Trep): Raghuraman et al. (2001) — Trep: 30.2 min.
Alvino et al. (2007) — Peak first observed at 15.0 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at XII-786 has unique ID: 727

Loading - Please wait...

ARS at XII-786 has unique ID: 727

Studies that cloned this origin

None curated.


Studies that analyzed this origin by 2D gel

None curated.


Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Xu et al. (2006): Chr12:785590-786915

Szilard et al. (2010): Chr12:786445-786455


Studies that measured the replication time of this origin

Raghuraman et al. (2001): Chr12:793602 (Trep: 30.2 min.) (Confidence: 9)

Alvino et al. (2007): Chr12:793860 (Peak first observed at 15.0 min.)


Studies that measured the activity of this origin in hydroxyurea (HU)

Crabbé et al. (2010): Chr12:785588-786917 (Activity detected in: ctf4, pol2-12, elg1, tof1, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)


Studies that predicted the location of this origin

This origin has not been predicted by any curated study.



ARS at XII-786 has unique ID: 727

Studies that confirmed an essential ACS element

None curated.


Studies that predicted an essential ACS element

  Xu et al. (2006):      ATTTTTTATATTTGGTATAACCGCTGAAGGTTAT  
ACS LOGO:   ACS_logo  

ARS at XII-786 has unique ID: 727

Alignments from the UCSC genome browser

No phylogenetic sequence conservation data.

ARS at XII-786 has unique ID: 727

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at XII-786 has unique ID: 727

Genome-wide studies that identified this origin

Raghuraman et al. (2001): PubMed | Science

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Szilard et al. (2010): PubMed | PubMed Central | Nat. Struct. Mol. Biol.

Crabbé et al. (2010): PubMed | Nat. Struct. Mol. Biol.


Studies that cloned this origin

None identified.


Studies that analyzed this origin by 2D gel

None identified.


Studies that confirmed an essential ACS element

None identified.


Studies that predicted an essential ACS element

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics


ARS at XII-786 has unique ID: 727