ARS212

Status: Confirmed ARS: Confirmed by ARS assay and identified by 5 genome-wide studies.

Genomic Location: Chr2:378434-379194
Within tandem intergenic space between YBR069C and YBR070C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence: View sequence

Origin Sequence Elements: ACS predicted.

Helical Stability: Minimum -170.1 ΔG° (kcal/mol) at location 378754.

Time of Origin Replication (Trep): Alvino et al. (2007) — Peak first observed at 12.5 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at II-379 has unique ID: 39

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ARS at II-379 has unique ID: 39

Studies that cloned this origin

Xu et al. (2006): Chr2:378434-379194

Studies that analyzed this origin by 2D gel

None curated.

Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Wyrick et al. (2001): Chr2:379180-379871

Xu et al. (2006): Chr2:378175-379925

Szilard et al. (2010): Chr2:379045-379055

Studies that measured the replication time of this origin

Alvino et al. (2007): Chr2:382330 (Peak first observed at 12.5 min.)

Studies that measured the activity of this origin in hydroxyurea (HU)

Crabbé et al. (2010): Chr2:378434-379194 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)

Studies that predicted the location of this origin

This origin has not been predicted by any curated study.

ARS at II-379 has unique ID: 39

Studies that confirmed an essential ACS element

None curated.

Studies that predicted an essential ACS element

Xu et al. (2006):

G

C

A

T

C

A

A

A

G

A

A

G

G

T

G

C

G

G

T

G

C

C

A

C

C

A

T

A

A

G

A

C

T

T

ACS LOGO:

ARS at II-379 has unique ID: 39

Alignments from the UCSC genome browser

ARS at II-379 has unique ID: 39

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at II-379 has unique ID: 39

Genome-wide studies that identified this origin

Wyrick et al. (2001): PubMed | Science

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Szilard et al. (2010): PubMed | PubMed Central | Nat. Struct. Mol. Biol.

Crabbé et al. (2010): PubMed | Nat. Struct. Mol. Biol.

Studies that cloned this origin

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Studies that analyzed this origin by 2D gel

None identified.

Studies that confirmed an essential ACS element

None identified.

Studies that predicted an essential ACS element

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

ARS at II-379 has unique ID: 39