Likely ARS at V-18

No systematic name assigned

Other names: proARS506

Status: Likely ARS: Identified by 6 genome-wide studies.

Genomic Location: Chr5:17067-19023
Probably within tandem intergenic space between YEL071W and YEL070W.
View at UCSC genome browser
View on SGD Chromosome Features Map
View at SGD gbrowser site
View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -158.2 ΔG° (kcal/mol) at location 17507.

Time of Origin Replication (Trep): Alvino et al. (2007) — Peak first observed at 12.5 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at V-18 has unique ID: 172

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ARS at V-18 has unique ID: 172

Studies that cloned this origin

None curated.


Studies that analyzed this origin by 2D gel

None curated.


Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Wyrick et al. (2001): Chr5:17845-18717

Xu et al. (2006): Chr5:17069-19021

Shor et al. (2009): Chr5:16400-17900 (orc2-1/wt peak ratio: 0.79)

Szilard et al. (2010): Chr5:18475-18485


Studies that measured the replication time of this origin

Alvino et al. (2007): Chr5:12778 (Peak first observed at 12.5 min.)


Studies that measured the activity of this origin in hydroxyurea (HU)

Crabbé et al. (2010): Chr5:18031-18531 (Activity detected in: ctf8, ctf18, mrc1, ctf18 rad9, mec1-100, rad53, mec1)


Studies that predicted the location of this origin

This origin has not been predicted by any curated study.



ARS at V-18 has unique ID: 172

Studies that confirmed an essential ACS element

None curated.


Studies that predicted an essential ACS element

None curated.

ACS LOGO:   ACS_logo  


ARS at V-18 has unique ID: 172

Alignments from the UCSC genome browser

No phylogenetic sequence conservation data.

ARS at V-18 has unique ID: 172

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at V-18 has unique ID: 172

Genome-wide studies that identified this origin

Wyrick et al. (2001): PubMed | Science

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Shor et al. (2009): PubMed | PubMed Central | PLoS Genet.

Szilard et al. (2010): PubMed | PubMed Central | Nat. Struct. Mol. Biol.

Crabbé et al. (2010): PubMed | Nat. Struct. Mol. Biol.


Studies that cloned this origin

None identified.


Studies that analyzed this origin by 2D gel

None identified.


Studies that confirmed an essential ACS element

None identified.


Studies that predicted an essential ACS element

None identified.


ARS at V-18 has unique ID: 172