ARS503

Status: Confirmed ARS: Confirmed by ARS assay and identified by 7 genome-wide studies.

Genomic Location: Chr5:6464-7230
Within tandem intergenic space between YEL075C and YEL073C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence: View sequence

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -149.9 ΔG° (kcal/mol) at location 6891.

Time of Origin Replication (Trep): Alvino et al. (2007) — Peak first observed at 12.5 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at V-7 has unique ID: 169

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ARS at V-7 has unique ID: 169

Studies that cloned this origin

Study details not curated: Chr5:6464-7230

Studies that analyzed this origin by 2D gel

None curated.

Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Wyrick et al. (2001): Chr5:6464-7230

Xu et al. (2006): Chr5:6029-7767

Shor et al. (2009): Chr5:6200-7500 (orc2-1/wt peak ratio: 0.76)

Szilard et al. (2010): Chr5:6875-6885

Müller et al. (2010): Chr5:6125-7325 (orc1-bah-delta/wt peak ratio: 0.62)

Studies that measured the replication time of this origin

Alvino et al. (2007): Chr5:12778 (Peak first observed at 12.5 min.)

Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr5:7500 (Activity detected in: rad53)

Studies that predicted the location of this origin

This origin has not been predicted by any curated study.

ARS at V-7 has unique ID: 169

Studies that confirmed an essential ACS element

None curated.

Studies that predicted an essential ACS element

None curated.

ACS LOGO:

ARS at V-7 has unique ID: 169

Alignments from the UCSC genome browser

ARS at V-7 has unique ID: 169

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at V-7 has unique ID: 169

Genome-wide studies that identified this origin

Wyrick et al. (2001): PubMed | Science

Feng et al. (2006): PubMed | PubMed Central | Nat. Cell Biol.

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Shor et al. (2009): PubMed | PubMed Central | PLoS Genet.

Szilard et al. (2010): PubMed | PubMed Central | Nat. Struct. Mol. Biol.

Müller et al. (2010): PubMed | PubMed Central | Genes Dev.

Studies that cloned this origin

None identified.

Studies that analyzed this origin by 2D gel

None identified.

Studies that confirmed an essential ACS element

None identified.

Studies that predicted an essential ACS element

None identified.

ARS at V-7 has unique ID: 169