Likely ARS at IV-477

No systematic name assigned

Status: Likely ARS: Identified by 5 genome-wide studies.

Genomic Location: Chr4:476003-477577
Probably within convergent intergenic space between YDR014W and YDR016C.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -150.2 ΔG° (kcal/mol) at location 476083.

Time of Origin Replication (Trep): Yabuki et al. (2002) — Trep: 22.2 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at IV-477 has unique ID: 111

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ARS at IV-477 has unique ID: 111

Studies that cloned this origin

None curated.


Studies that analyzed this origin by 2D gel

None curated.


Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Xu et al. (2006): Chr4:476005-477575

Szilard et al. (2010): Chr4:476665-476675


Studies that measured the replication time of this origin

Yabuki et al. (2002): Chr4:478791 (Trep: 22.2 min.)

Alvino et al. (2007): Chr4:481870 (Peak first observed at 12.5 min.)


Studies that measured the activity of this origin in hydroxyurea (HU)

Crabbé et al. (2010): Chr4:476003-477577 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ctf4, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)


Studies that predicted the location of this origin

This origin has not been predicted by any curated study.



ARS at IV-477 has unique ID: 111

Studies that confirmed an essential ACS element

None curated.


Studies that predicted an essential ACS element

None curated.

ACS LOGO:   ACS_logo  


ARS at IV-477 has unique ID: 111

Alignments from the UCSC genome browser

No phylogenetic sequence conservation data.

ARS at IV-477 has unique ID: 111

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at IV-477 has unique ID: 111

Genome-wide studies that identified this origin

Yabuki et al. (2002): PubMed

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Szilard et al. (2010): PubMed | PubMed Central | Nat. Struct. Mol. Biol.

Crabbé et al. (2010): PubMed | Nat. Struct. Mol. Biol.


Studies that cloned this origin

None identified.


Studies that analyzed this origin by 2D gel

None identified.


Studies that confirmed an essential ACS element

None identified.


Studies that predicted an essential ACS element

None identified.


ARS at IV-477 has unique ID: 111