Likely ARS at XIV-253

No systematic name assigned

Status: Likely ARS: Identified by 6 genome-wide studies.

Genomic Location: Chr14:252383-254147
Probably within tandem intergenic space between YNL209W and YNL208W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -161.3 ΔG° (kcal/mol) at location 252533.

Time of Origin Replication (Trep): Raghuraman et al. (2001) — Trep: 29.1 min.
Yabuki et al. (2002) — Trep: 29.0 min.
Alvino et al. (2007) — Peak first observed at 17.5 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at XIV-253 has unique ID: 741

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ARS at XIV-253 has unique ID: 741

Studies that cloned this origin

None curated.


Studies that analyzed this origin by 2D gel

Aparicio et al. (2004): Chr14:247554-252796

Gibson et al. (2004): Chr14:247554-252796


Studies that detected this origin by chromatin immunoprecipitation (ChIP)

Xu et al. (2006): Chr14:252385-254145

Shor et al. (2009): Chr14:252800-254100 (orc2-1/wt peak ratio: 1.02)


Studies that measured the replication time of this origin

Raghuraman et al. (2001): Chr14:250798 (Trep: 29.1 min.) (Confidence: 5)

Yabuki et al. (2002): Chr14:249469 (Trep: 29.0 min.)

Alvino et al. (2007): Chr14:251200 (Peak first observed at 17.5 min.)


Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr14:249333 (Activity detected in: rad53)


Studies that predicted the location of this origin

This origin has not been predicted by any curated study.



ARS at XIV-253 has unique ID: 741

Studies that confirmed an essential ACS element

None curated.


Studies that predicted an essential ACS element

None curated.

ACS LOGO:   ACS_logo  


ARS at XIV-253 has unique ID: 741

Alignments from the UCSC genome browser

No phylogenetic sequence conservation data.

ARS at XIV-253 has unique ID: 741

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at XIV-253 has unique ID: 741

Genome-wide studies that identified this origin

Raghuraman et al. (2001): PubMed | Science

Yabuki et al. (2002): PubMed

Feng et al. (2006): PubMed | PubMed Central | Nat. Cell Biol.

Xu et al. (2006): PubMed | PubMed Central | BMC Genomics

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Shor et al. (2009): PubMed | PubMed Central | PLoS Genet.


Studies that cloned this origin

None identified.


Studies that analyzed this origin by 2D gel

Aparicio et al. (2004): PubMed | PubMed Central | Mol. Cell. Biol.

Gibson et al. (2004): PubMed | PubMed Central | Mol. Cell. Biol.


Studies that confirmed an essential ACS element

None identified.


Studies that predicted an essential ACS element

None identified.


ARS at XIV-253 has unique ID: 741