Status: Confirmed ARS: Confirmed by ARS assay and identified by 4 genome-wide studies.
Genomic Location:
Chr12:458826-459141
Within divergent intergenic space between RDN18-1 and RDN5-1.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
DNA Sequence:
Origin Sequence Elements: ACS confirmed.
Helical Stability: Minimum -154.4 ΔG° (kcal/mol) at location 458876.
Time of Origin Replication (Trep): This site was not identified as an origin by any curated timing study (Raghuraman et al. (2001); Yabuki et al. (2002); Alvino et al. (2007)), suggesting that this site is not chromosomally active for replication initiation.
Origin activity in HU: Origin activity not detected in HU.
ARS at XII-459 has unique ID: 417
ARS at XII-459 has unique ID: 417
Chr12:458826-459141
None curated.
Chr12:457095-460755
Chr12:449900-469200 (orc2-1/wt peak ratio: 0.67)
Chr12:458905-458915
Chr12:458525-460325 (orc1-bah-delta/wt peak ratio: 0.24)
The replication time of origin has not be reported by any curated study.
This origin has not be reported as active in HU by any curated study.
This origin has not been predicted by any curated study.
ARS at XII-459 has unique ID: 417
| Nieduszynski et al. (2006): | G | T | T | T | A | T | G | T | T | T | T |
| Xu et al. (2006): | A | T | T | G | T | T | T | A | T | G | T | T | T | T | G | T | G | T | G | A | T | G | A | T | T | T | T | A | C | A | T | T | T | T | ||||||||
| Xu et al. (2006): | C | T | A | T | T | C | T | A | T | G | T | T | T | T | C | T | T | A | C | T | C | C | T | A | T | G | T | C | T | A | T | T | C | A | ||||||||
| ACS LOGO: |  | |||||||||||||||||||||||||||||||||||||||||
ARS at XII-459 has unique ID: 417
| Confirmed ACS | |||||||||||||||||||||||||||||||||||||||||||||||||||
| S. cerevisiae | G | G | A | A | A | T | G | G | C | T | G | A | T | T | T | T | G | A | T | T | G | T | T | T | A | T | G | T | T | T | T | G | T | G | T | G | A | T | G | A | T | T | T | T | A | C | A | T | T | T | T |
| S. kudriavzevii | G | G | A | A | A | A | G | T | T | A | G | A | T | A | T | T | G | A | T | T | G | T | T | T | A | T | G | T | C | T | T | G | T | G | T | G | A | T | A | T | T | T | T | T | A | C | A | T | T | T | T |
| S. mikatae | G | G | A | A | A | A | G | G | T | A | G | A | C | A | T | T | G | T | T | T | G | T | T | T | A | T | G | T | C | T | T | G | T | A | T | G | A | T | A | T | T | T | T | T | A | C | A | T | T | T | T |
| S. paradoxus | G | G | A | A | A | A | G | G | T | C | T | A | T | T | T | T | G | T | T | T | G | T | T | T | A | T | G | T | C | T | T | G | T | G | T | G | A | T | A | A | T | T | T | T | A | C | A | T | T | T | T |
| S. bayanus | G | G | A | A | A | G | C | T | T | G | G | A | T | A | T | T | G | T | T | T | G | T | T | T | A | T | G | T | C | T | T | G | T | G | T | G | A | T | A | T | T | T | T | T | A | C | A | T | T | T | T |
| * | * | * | * | * | : | : | : | : | : | * | : | * | * | * | * | * | * | * | * | * | * | * | * | * | : | * | * | * | * | : | * | * | * | * | : | * | * | * | * | * | * | * | * | * | * | * | |||||
ARS at XII-459 has unique ID: 417
These notes are manually curated. To submit notes for this replication origin site please contact us.
There are no notes entered for this replication origin site.
ARS at XII-459 has unique ID: 417
PubMed | PubMed Central | BMC Genomics
PubMed | PubMed Central | PLoS Genet.
PubMed | PubMed Central | Nat. Struct. Mol. Biol.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | Genes Dev.
None identified.
PubMed | PubMed Central | Genes Dev.
PubMed | PubMed Central | BMC Genomics
ARS at XII-459 has unique ID: 417
