Status: Dubious ARS: Identified by 6 genome-wide studies.
Origin Sequence Elements: No elements have been reported for this origin.
Helical Stability: Minimum -159.4 ΔG° (kcal/mol) at location 326413.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 25.5 min.
Yabuki et al. (2002) — Trep: 21.6 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity detected in HU — more details.
Chr11:326000-327100 (orc2-1/wt peak ratio: 1.21)
Chr11:325415 (Trep: 25.5 min.) (Confidence: 8)
Chr11:329002 (Trep: 21.6 min.)
Chr11:329440 (Peak first observed at 12.5 min.)
Chr11:329000 (Activity detected in: wild-type, rad53)
This origin has not been predicted by any curated study.
These notes are manually curated. To submit notes for this replication origin site please contact us.
Friday, 4th December 2009 - Conrad Nieduszynski:
Status manually changed to 'Dubious'. Shor et al. (2009) report that there is no detectable ARS activity in this region.