Status: Dubious ARS: Identified by 5 genome-wide studies.
Probably within tandem intergenic space between YHR174W and YHR175W.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser
Origin Sequence Elements: No elements have been reported for this origin.
Helical Stability: Minimum -165.2 ΔG° (kcal/mol) at location 451613.
Time of Origin Replication (Trep):
Raghuraman et al. (2001) — Trep: 25.4 min.
Yabuki et al. (2002) — Trep: 20.9 min.
Alvino et al. (2007) — Peak first observed at 12.5 min.
Origin activity in HU: Origin activity not detected in HU.
Chr8:451400-452900 (orc2-1/wt peak ratio: 1.09)
Chr8:447627 (Trep: 25.4 min.) (Confidence: 9)
Chr8:447835 (Trep: 20.9 min.)
Chr8:446780 (Peak first observed at 12.5 min.)
This origin has not be reported as active in HU by any curated study.
This origin has not been predicted by any curated study.
These notes are manually curated. To submit notes for this replication origin site please contact us.
Friday, 4th December 2009 - Conrad Nieduszynski:
Status manually changed to 'Dubious'. Shor et al. (2009) report that there is no detectable ARS activity in this region.