Confirmed ARS at XII-687

ARS1220.5

Status: Confirmed ARS: Confirmed by ARS assay and identified by 3 genome-wide studies.

Genomic Location: Chr12:687249-687738
Within tandem intergenic space between YLR272C and TV(AAC)L.
• View at UCSC genome browser
• View on SGD Chromosome Features Map
• View at SGD gbrowser site
• View at Ensembl browser

DNA Sequence:

Origin Sequence Elements: No elements have been reported for this origin.

Helical Stability: Minimum -147.1 ΔG° (kcal/mol) at location 687679.

Time of Origin Replication (Trep): Alvino et al. (2007) — Peak first observed at 10.0 min.

Origin activity in HU: Origin activity detected in HU — more details.

ARS at XII-687 has unique ID: 426

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ARS at XII-687 has unique ID: 426

Studies that cloned this origin

Müller & Nieduszynski (2012): Chr12:687249-687738


Studies that analyzed this origin by 2D gel

None curated.


Studies that detected this origin by chromatin immunoprecipitation (ChIP)

None curated.


Studies that measured the replication time of this origin

Alvino et al. (2007): Chr12:685110 (Peak first observed at 10.0 min.)


Studies that measured the activity of this origin in hydroxyurea (HU)

Feng et al. (2006): Chr12:688000 (Activity detected in: rad53)

Crabbé et al. (2010): Chr12:687294-687794 (Activity detected in: wild-type, rad9, rev3 rad30, eco1, ddc1, rad24, pol2-12, elg1, tof1, mrc1-AQ, mrc1-AQ rad9, ctf8, ctf18, mrc1, dcc1, ctf18 rad9, mec1-100, rad53, mec1)


Studies that predicted the location of this origin

This origin has not been predicted by any curated study.



ARS at XII-687 has unique ID: 426

Studies that confirmed an essential ACS element

None curated.


Studies that predicted an essential ACS element

None curated.

ACS LOGO:   ACS_logo  


ARS at XII-687 has unique ID: 426

Alignments from the UCSC genome browser

No phylogenetic sequence conservation data.

ARS at XII-687 has unique ID: 426

These notes are manually curated. To submit notes for this replication origin site please contact us.

There are no notes entered for this replication origin site.

ARS at XII-687 has unique ID: 426

Genome-wide studies that identified this origin

Feng et al. (2006): PubMed | PubMed Central | Nat. Cell Biol.

Alvino et al. (2007): PubMed | PubMed Central | Mol. Cell. Biol.

Crabbé et al. (2010): PubMed | Nat. Struct. Mol. Biol.


Studies that cloned this origin

Müller & Nieduszynski (2012): PubMed | Genome Res.


Studies that analyzed this origin by 2D gel

None identified.


Studies that confirmed an essential ACS element

None identified.


Studies that predicted an essential ACS element

None identified.


ARS at XII-687 has unique ID: 426