OriDB Curated Paper

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Strategies for analyzing highly enriched IP-chip datasets.

Simon R V Knott, Christopher J Viggiani, Oscar M Aparicio, Simon Tavaré

BMC Bioinformatics (2009), 10(0):305PubMed | PubMed Central | BMC Bioinformatics

Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been employed to examine features such as protein binding and histone modifications on a genome-wide scale in a variety of cell types. Array data from the latter studies typically have a high proportion of enriched probes whose signals vary considerably (due to heterogeneity in the cell population), and this makes their normalization and downstream analysis difficult.

OriDB annotation of this paper:

ARS assay

None curated.

2D gel

None curated.

ChIP of replication origin proteins

None curated.

Replication timing

None curated.

Replication in hydroxyurea

None curated.

Predicted origins

None curated.

Confirmed sequence element

None curated.

Predicted sequence element

None curated.

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